1. Prepare the injection site.
Semaglutide is administered subcutaneously to the abdomen, thigh, or upper arm.
Choose the area where you plan to give the shot. Wipe the area with an alcohol pad and let it dry for a few seconds. Make sure to use a different injection site each week when injecting in the same body region.

2. Inject semaglutide.
Subcutaneous injections can be given at a 90-degree angle or a 45-degree angle. The injection can be done at a 90-degree angle if 2 inches of skin can be grasped between your thumb and index finger. If only 1 inch of skin can be grasped, inject at a 45-degree angle.
Grasp the skin with the hand not holding the syringe to create a fat fold. Holding the syringe securely with the other hand, insert the needle under the skin. When the needle is fully inserted, slowly push down on the plunger to inject the contents of the syringe. Pull out the needle at the same angle it went in.
Safely dispose of the needle.

The content in this file, including text, images, and other content, is provided for general information purposes only and does not constitute medical advice.

Important Information
Frequency of Semaglutide Injections
Administer semaglutide once a week, on the same day each week. You can give an injection at any time of the day, with or without meals.
The day of the weekly injection can be changed if necessary as long as the time between two doses is at least 48 hours.

Semaglutide Missed Dose
Don’t worry if you missed your semaglutide injection. Give yourself a shot as soon as possible within 5 days after the missed dose.
If more than 5 days have passed, it is recommended to skip the missed dose and administer the next semaglutide dose on the regularly scheduled day.

How to Store Semaglutide
Semaglutide is a thermolabile product. It should be stored in a refrigerator to retain its properties. However, leaving semaglutide at room temperature for a while or exposure to moderate heat will not instantly make it useless.